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静岡県立大学教員データベース


教員情報詳細


写真:鈴木 隆

氏名
鈴木 隆(SUZUKI Takashi)
所属・職名
薬学部薬学科(生化学分野) 教授
薬学研究院(生化学教室) 教授(兼務)
薬学研究院長
Eメールアドレス
suzukit(ここに@を入れてください)u-shizuoka-ken.ac.jp
ホームページアドレス(URL)
http://w3pharm.u-shizuoka-ken.ac.jp/biochem/
研究シーズ集
http://www.u-shizuoka-ken.ac.jp/file/1tsuzuki.pdf

学歴

1979年3月 静岡薬科大学薬学科卒業
1981年3月 静岡薬科大学大学院薬学研究科修士課程修了
1984年3月 静岡薬科大学大学院薬学研究科博士課程修了


学位

薬学博士(静岡薬科大学・1984年)


専門分野

生化学、糖鎖生物学、ウイルス学


担当科目

【学部担当科目】生物化学Ⅲ、生物化学Ⅳ、ウイルス学、生物学入門、薬学基礎・医用工学実習、生物系薬学実習Ⅰ、Ⅱ
【大学院担当科目】生化学特論、講座特別演習、薬学特別実験


主要研究テーマ

生体における複合糖質および関連分子の機能解明
1. ウイルス感染増殖における糖鎖の機能解明
2. ウイルス表面糖タンパク質に関する研究
3. ウイルス受容体構造情報に基づく抗ウイルス剤設計
4. 中枢神経における糖鎖の機能解明
5. 細胞表面糖鎖分子の発現制御に関する研究


所属学会

日本薬学会(代議員)
日本生化学会
日本糖質学会(評議員)
日本ウイルス学会(評議員)
日本脂質生化学会(幹事)
米国微生物学会
日本癌学会


主な経歴

1984年 シノテスト研究所
1991年 静岡県立大学助手
1994年 静岡県立大学講師
1996年 静岡県立大学助教授
1997~1998年 米国 St. Jude Children’s Research Hospital 客員研究員
1998~1999年 米国 St. Jude Children’s Research Hospital 客員研究員(文部省在外研究員)
2006年 静岡県立大学教授


受賞歴

2012年 O-CHAパイオニア賞 学術研究大賞
平成29年度日本薬学会学術貢献賞


主な社会活動

2000~2001年 日本薬学会東海支部幹事
2000~2001年 ファルマシア地区通信員
2015~2017年日本糖質学会評議員
2008~2009年 日本薬学会東海支部幹事
2016~2017年 日本薬学会代議員
2012年~ 日本ウイルス学会評議員
2016年~2019年 日本脂質生化学会幹事


主要研究業績

○学術論文
1) Rapid regulation of sialidase activity in response to neural activity and sialic acid removal during memory processing in rat hippocampus
J Biol Chem. in press
2) Role of sialidase in long-term potentiation at mossy fiber-CA3 synapses and hippocampus-dependent spatial memory
PLoS One 11, e0165257 (2016)
3) High-efficiency capture of drug resistant-influenza virus by live imaging of sialidase activity
PLoS One 11(5): e0156400 (2016)
4) Polyacrylamide backbones for polyvalent bioconjugates using “post-click” chemistry
Polym. Chem. 7, 5920-5924 (2016)
5) Easy and Rapid Detection of Mumps Virus by Live Fluorescent Visualization of Virus-Infected Cells
PLoS One 10, e0144038 (2015) doi:10.1371/journal.pone.0144038
6) Preferential accumulation of 14C-N-glycolylneuraminic acid over 14C-N-acetylneuraminic acid in the rat brain after tail vein injection.
PLoS One 10, e0131061 (2015) doi:10.1371/journal.pone.0131061
7) Isolation and characterization of monoclonal antibodies specific for chondroitin sulfate E.
Glycobiology 25, 953-962 (2015) doi: 10.1093/glycob/cwv039
8) Production and purification of secretory simian cytidine monophosphate-N-acetyl neuraminic acid hydroxylase by using baculovirus-protein expression system.
Biol. Pharm. Bull. 38, 1220-1226 (2015) doi:10.1248/bpb.b15-00299
9) Fluorescent detection assay for human parainfluenza viruses.
Biol. Pharm. Bull. 38, 1214-1219 (2015) doi:10.1248/bpb.b15-00298
10) Amino acid substitutions contributing to α2,6-sialic acid linkage binding specificity of human parainfluenza virus type 3 hemagglutinin-neuraminidase.
FEBS Lett. 589, 1278-1282 (2015) doi:10.1016/j.febslet.2015.03.036.
11) Consecutive oral administration of Bifidobacterium longum MM-2 improves the defense system against influenza virus infection by enhancing natural killer cell activity in a murine model.
Microbiol. Immunol. 59, 1-12 (2015) doi: 10.1111/1348-0421.12210.
12) A novel immunochromatographic system for easy-to-use detection of group 1 avian influenza viruses with acquired human-type receptor binding specificity.
Biosens. Bioelectron. 65, 211-219 (2014)
13) Protecting-group-free Synthesis of Glycopolymers Bearing Sialyloligosaccharide and their High Binding with Influenza Virus.
ACS Macro Lett. 3, 1074-1078 (2014)
14) A novel method for detection of Newcastle disease virus with a fluorescent sialidase substrate.
J. Virol. Methods 209, 136-142 (2014)
15) Histochemical imaging of alkaline phosphatase using a novel fluorescent substrate.
Biol. Pharm. Bull. 37, 1668-1673 (2014)
16) Terminal Sialic Acid Linkages Determine Different Cell Infectivities of Human Parainfluenza Virus Type 1 and Type 3.
Virology 464-465, 424-431 (2014)
17) Computational design of a sulfoglucuronide derivative fitting into a hydrophobic pocket of dengue virus E protein.
Biochem. Biophys. Res. Commun. 449, 32-37 (2014)
18) N-glycolylneuraminic Acid on Human Epithelial Cells Prevents Entry of Influenza A Virus with N-glycolylneuraminic Acid Binding Ability.
J. Virol. 88, 8445-8456 (2014)
19) Imaging of influenza virus sialidase activity in living cells.
Sci. Rep., 4, 4877 (2014)
20) Histochemical fluorescent staining of Sendai virus-infected cells with a novel sialidase substrate.
Virology 464-465, 206-212 (2014)
21) Visualization of sialidase activity in mammalian tissues and cancer detection with a novel fluorescent sialidase substrate.
PLoS ONE 9, e81941 (2014)
22) Visualization of sialidase activity in mammalian tissues and cancer detection with a novel fluorescent sialidase substrate.
PLoS ONE 9, e81941 (2014)
23) Improvement of depression-like behavior and memory impairment with the ethanol extract of Pleurotus eryngii in ovariectomized rats.
Biol. Pharm. Bull. 36, 1990-1995 (2013)
24) Sensitive and direct detection of receptor binding specificity of highly pathogenic avian influenza A virus in clinical samples.
PLoS ONE 8, e78125 (2013)
25) Influenza virus utilizes N-linked sialoglycans as receptors in A549 cells.
Biochem. Biophys. Res. Commun. 436, 394-399 (2013)
26) Catalytic preference of Salmonella typhimurium LT2 sialidase for N-acetylneuraminic acid residue over N-glycolylneuraminic acid residue.
FEBS Open Bio 3, 231-236 (2013)
27) 2-(Benzothiazol-2-yl)-phenyl-β-D-galactopyranoside derivatives as fluorescent pigment dyeing substrates and their application for the assay of β-D-galactosidase activities.
Bioorg. Med. Chem. Lett. 23, 2245-2249 (2013)
28) Amino acid determinants conferring stable sialidase activity at low pH for H5N1 influenza A virus neuraminidase.
FEBS Open Bio 2, 261-266 (2012)
29) Design and Synthesis of a Novel Ganglioside Ligand for Influenza A Viruses.
Molecules. 17, 9590-9620 (2012)
30) 3-O-sulfated glucuronide derivative as a potential anti-dengue virus agent.
Biochem. Biophys. Res. Commun. 424, 573-578 (2012)
31) Sulfatide Negatively Regulates the Fusion Process of Human Parainfluenza Virus Type 3.
J. Biochem. 152, 373-380 (2012)
32) No evidence of horizontal infection in horses kept in close contact with dogs experimentally infected with canine influenza A virus (H3N8).
Acta Vet. Scand. 54, 25 (2012)
33) Origins of the inhibitory activity of 4-O-substituented sialic derivatives of human parainfluenza virus.
Glycoconj. J. 29, 231-237 (2012)
34) Comparative Analyses of N-Glycosylation Profiles of Influenza A Viruses Grown in Different Host Cells.
Open Glycoscience 5, 2-12 (2012)
35) Cold-shock protein expression system facilitates the solubility of human ST6Gal I in Escherichia coli.
Open Glycoscience 5, 13-18 (2012)
36) Adaptation of a duck influenza A virus in quail.
J. Virol. 86, 1411-1420 (2012)
37) Imaging of sialidase activity in rat brain sections by a highly sensitive fluorescent histochemical method.
NeuroImage 58, 34-40 (2011)
38) Plaque formation assay for human parainfluenza virus type 1.
Biol. Pharm. Bull. 34, 996-1000 (2011)
39) A single amino acid mutation at position 170 of human parainfluenza virus type 1 fusion glycoprotein induces obvious syncytium formation and caspase-3-dependent cell death.
J. Biochem. 149, 191-202 (2011)
40) The Low-pH Stability Discovered in Neuraminidase of 1918 Pandemic Influenza A Virus Enhances Virus Replication.
PLoS One 5 (12), e15556 (2010)
41) Influenza A (H5N1) viruses from pigs, Indonesia
Emerg. Infect. Dis. 16, 1515-1523 (2010)
42) Antiviral activity of chondroitin sulphate E targeting dengue virus envelope protein
Antiviral Res. 88, 236-243 (2010)
43) Infectivity and pathogenicity of canine H3N8 influenza a virus in horses
Influenza Other Respi. Viruses 4, 345-351 (2010)
44) Antiviral effect of strictinin on influenza virus replication
Antiviral Res. 88, 10-18 (2010)
45) Binding of sulfatide to recombinant hemagglutinin of influenza A virus produced by a baculovirus protein expression system.
J. Biochem. 147, 459-462 (2010)
46) Identification of amino acid residues of influenza A virus H3 HA contributing to the recognition of molecular species of sialic acid.
FEBS Lett. 583, 3171-3174 (2009)
47) Mechanisms of the action of povidone-iodine against human and avian influenza A viruses: its effects on hemagglutination and sialidase activities.
Virol. J. 6, 124 (2009)
48) Systematic syntheses of influenza neuraminidase inhibitors: A series of carbosilane dendrimers uniformly functionalized with thioglycoside-type sialic acid moieties.
Bioorg. Med. Chem. 17, 5451-5464 (2009)
49) Molecular Design of Spacer-N-Linked Sialoglycopolypeptide as Polymeric Inhibitors Against Influenza Virus Infection.
Biomacromolecules 10, 1894-1903 (2009)
50) Glucosyl Hesperidin Prevents Influenza A Virus Replication In Vitro by Inhibition of Viral Sialidase.
Biol. Pharm. Bull. 32, 1188-1192 (2009)
51) Identification and characterization of flavonoids as sialyltransferase inhibitors.
Biochem. Biophys. Res. Commun. 382, 609-613 (2009)
52) Chemoenzymatic Synthesis of Sialoglycopolypeptides As Glycomimetics to Block Infection by Avian and Human Influenza Viruses.
Bioconjugate. Chem., 20, 538–549 (2009)
53) Surface localization of the nuclear receptor CAR in influenza A virus-infected cells.
Biochem. Biophys. Res. Commun., 368, 550-555 (2008)
54) In Vitro Inhibition of Human Influenza A Virus Infection by Fruit-Juice Concentrate of Japanese Plum (Prunus mume Sieb. et Zucc).
Biol. Pharm. Bull., 31, 511-515 (2008)
55) Clarithromycin Inhibits Progeny Virus Production from Human Influenza Virus-infected Host Cells.
Biol. Pharm. Bull., 31, 217-222 (2008)
56) The expression of sialylated high-antennary N-glycans in edible bird’s nest.
Carbohydr. Res., 343, 1373-1377 (2008)
57) Sulfatide Is Required for Efficient Replication of Influenza A Virus.
J. Virol., 82, 5940-5950 (2008)
58) Chemoenzymatic synthesis, characterization, and application of glycopolymers carrying lactosamine repeats as entry inhibitors against influenza virus infection.
Glycobiology, 18, 779-788 (2008)
59) 2-Deoxy-2,3-didehydro-N-acetylneuraminic acid analogs structurally modified by thiocarbamoylalkyl groups at the C-4 position: Synthesis and biological evaluation as inhibitors of human parainfluenza virus type 1
Bioorg. Med. Chem., 16, 6783-6788 (2008)
60) Structure and anti-dengue virus activity of sulfated polysaccharide from a marine alga.
Biochem. Biophys. Res. Commun., 376, 91-95 (2008)
61) The quail and chicken intestine have sialyl-Gal sugar chains responsible for the binding of influenza A viruses to human type receptors.
Glycobiology 17, 713-724 (2007)
62) Synthesis of 4-O-[3-(aryl)prop-2-ynyl]-Neu5Ac2en and its 4-epi-analogs modified at C-4 by Sonogashira coupling reaction.
Tetrahedron 63, 7571-7581 (2007)
63) Concise synthesis of dideoxy-epigallocatechin gallate (DO-EGCG) and evaluation of its anti-influenza virus activity.
Bioorg. Med. Chem. Lett. 17, 3095-3098 (2007)
64) Synthesis and evaluation of 4-O-alkylated 2-deoxy-2,3-didehydro-N-acetylneuraminic acid derivatives as inhibitors of human parainfluenza virus type-3 sialidase activity.
Bioorg. Med. Chem. Lett. 17, 1655-1658 (2007)
65) Lactotriaose-containing carbosilane dendrimers: syntheses and lectin-binding activities.
Bioorg. Med. Chem., 15, 1606-1614 (2007)
66) Chemoenzymatic synthesis of artificial glycopolypeptides containing multivalent sialyloligosaccharides with a gamma-polyglutamic acid backbone and their effect on inhibition of infection by influenza viruses.
Bioorg. Med. Chem., 15, 1383-1393 (2007)
67) Thiosialoside clusters using carbosilane dendrimer core scaffolds as a new class of influenza neuraminidase inhibitors.
Bioorg. Med. Chem. Lett., 17, 717-721 (2007)
68) Novel linear polymers bearing thiosialosides as pendant-type epitopes for influenza neuraminidase inhibitors.
Bioorg. Med. Chem. Lett. 17, 3826–3830 (2007)
69) Hemagglutinin mutations responsible for the binding of H5N1 Influenza A Viruses to human-type receptors.
Nature 444, 378-382 (2006)
70) 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues structurally modified at the C-4 position: Synthesis and biological evaluation as inhibitors of human parainfluenza virus type1.
Bioorg. Med. Chem. 14, 7893-7897 (2006)
71) Suppression of the biosynthesis of cellular sphingolipids results in the inhibition of the maturation of influenza virus particles in MDCK cells.
Biol. Pharm. Bull. 29, 1575-1579 (2006)
72) Chemoenzymatic synthesis and application of a sialoglycopolymer with a chitosan backbone as a potent inhibitor of human influenza virus hemagglutination.
Carbohydr. Res. 341, 1803-1808 (2006)
73) Edible bird's nest extract inhibits influenza virus infection.
Antiviral Res. 70, 140-146 (2006)
74) Gangliosides are not essential for influenza virus infection.
Glycoconjugate J., 23, 107-113 (2006)
75) Identification and characterization of carbohydrate molecules in Mammalian cells recognized by dengue virus type 2.
J. Biochem. 139, 607-614 (2006)
76) Human trachea primary epithelial cells express both sialyl-2,3 Gal receptor for human parainfluenza virus type 1 and avian influenza viruses, and sialyl-2,6Gal receptor for human influenza viruses.
Glycoconjugate J., 23, 101-106 (2006)
77) Sulfatide and its synthetic analogues recognition by Moraxella catarrhalis.
Microbiol Immunol. 50, 967-970 (2006)
78) Design and Synthesis of Artificial Phospholipid for Selective Cleavage of Integral Membrane Protein.
Chem. Comm., 36, 4575-4577 (2005).
79) Sialidase activity of influenza A virus in a endocytic pathway enhances viral replication.
J. Virol., 79, 11705-11715 (2005).
80) Characterization of a human H5N1 influenza A virus isolated in 2003.
J Virol., 79, 9926-9932 (2005).
81) Isolation of drug-resistant H5N1 virus.
Nature, 437, 1108 (2005).
82) Antigenic alteration of influenza B virus associated with loss of a glycosylation site due to host-cell adaptation.
J. Med. Virol., 74, 336-343, (2004).
83) 2β,3β-Difluorosialic acid derivatives structurally modified at the C-4 position: synthesis and biological evaluation as inhibitors of human parainfluenza virus type 1.
Carbohydr. Res., 339, 1367-1372, (2004).
84) Design of N-acetyl-6-sulfo-β-D-glucosaminide-based inhibitors of influenza virus sialidase.
Bioorg. Med. Chem., 12, 1367-1375, (2004).
85) volutional analysis of human influenza A virus N2 neuraminidase genes based on the transition of the low-pH stability of sialidase activity.
FEBS. Lett., 557, 228-232, (2004).
86) Cerebroside sulfotransferase deficiency ameliorates L-selectin-dependent monocyte infiltration in the kidney after ureteral obstruction.
J. Biol. Chem., 279, 2085-2090, (2004).
87) Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus.
Nature, 431, 703-707 (2004).
88) Glycotentacles: synthesis of cyclic glycopeptides, toward a tailored blocker of influenza virus hemagglutinin.
Angew. Chem. Int. Ed., 42, 5186-5189, (2003).
89) Inhibition of influenza A virus sialidase activity by sulfatide.
FEBS Lett., 553, 355-359, (2003).
90) A molecular mechanism for the low-pH stability of sialidase activity of influenza A virus N2 neuraminidases.
FEBS Lett., 543, 71-75, (2003).
91) Ruthenium complexes carrying a disialo complex-type oligosaccharide: enzymatic synthesis and its application to a luminescent probe to detect influenza viruses.
Chem. Comm., 11, 1250-1251, (2003).
92) Chemoenzymatic synthesis and application of glycopolymers containing multivalent sialyloligosaccharides with a poly(L-glutamic acid) backbone for inhibition of infection by influenza viruses.
Glycobiol.,13, 315-326, (2003).
93) Oligosaccharides as receptors for JC virus.
J. Virol., 76, 12992-13000, (2002).
94) An O-glycoside of sialic acid derivative that inhibits both hemagglutinin and sialidase activities of influenza viruses.
Glycobiol., 12, 183-190, (2002).
95) Characterization of a human H9N2 influenza virus isolated in Hong Kong.
Vaccine, 20, 125-133, (2001).
96) A unique phosphatidylinositol bearing a novel branched-chain fatty acid from Rhodococcus equi binds to influenza virus hemagglutinin and inhibits the infection of cells.
J. Biochem., 130, 377-384, (2001).
97) Inhibition of human parainfluenza virus type 1 neuraminidase by analogues of 2-deoxy-2,3-didehydro-N-acetyl-neuraminic aicd.
Glycoconjugate J., 18, 331-337, (2001).
98) Duck and human pandemic influenza A viruses retain sialidase activity in low pH conditions.
J. Biochem., 130, 279-283, (2001).
99) Receptor Specificities of the Human Respiroviruses.
J. Virol., 75, 4604-4613, (2001).
100) Engagement of endogenous ganglioside GM1a induces tyrosine phosphorylation involved in neuron-like differentiation of PC12 cells.
Glycobiol., 11, 335-343, (2001).
101) Adaptation of Influenza A viruses to cells expressing low levels of sialic acid leads to loss of neuraminidase activity.
J. Virol., 75, 3766-3770, (2001).
102) Sialic acid species as a determinant of the host range of influenza A viruses.
J. Virol., 74, 11825-11831, (2000).
103) Recognition of N-glycolylneuraminic acid linked to galactose by the 2,3 linkage is associated with the intestinal replication of influenza A virus in ducks.
J. Virol., 74, 9300-9305, (2000).

○総説
1) Protecting-Group-Free Synthesis of Glycopolymers and Their Binding Assay with Lectin and Influenza Virus.
Methods Mol. Biol. (Springer Publishing) 1367, 39-48 (2016) doi: 10.1007/978-1-4939-3130-9_4
2) Low-pH Stability of Influenza A Virus Sialidase Contributing to Virus Replication and Pandemic.
Biol. Pharm. Bull. 38, 817-826 (2015)
3) Role of Sulfatide in Influenza A virus Replication.
Biol. Pharm. Bull. 38, 809-816 (2015)
4) Role of glycans in viral infection.
Sugar Chains, Springer Publishing, p. 71-93 (2015)
5) Binding of influenza viruses to glycans.
Glycoscience: Biology and Medicine (Part IIIV, Microbial Glycobiology and Infection, Glycobiology: Role of Glycans in Infections), Springer Publishing, pp 769-774 (2014)
6) 緑茶によるインフルエンザウイルスの予防効果
ファルマシア, 49,1080-1084 (2013)
7) Role of sulfatide in normal and pathological cells and tissues.
J. Lipid Res. i53, 1437-1450 (2012)
8) Activity and the Role of Sialidase in the Brain. -脳におけるシアリダーゼの活性分布と役割-
Trends in Glycoscience and Glycotechnology Vol. 24 (No. 137), 112-121 (2012)
9) Antiviral agents targeting glycans on dengue virus E-glycoprotein.
Expert. Rev. Anti. Infect. Ther. 9, 983-985 (2011)
10) Function of membrane rafts in viral lifecycles and host cellular response.
Biochem. Res. Int. 2011, 245090(2011)
11) Antiviral agents targeting glycans on dengue virus E-glycoprotein.
Expert. Rev. Anti. Infect. Ther. 9, 983-985 (2011)
12) 抗インフルエンザ薬について
実験治療, 699, 48-54(2010)
13) インフルエンザウイルス感染の化学的理解に向けて-宿主細胞からの放出-現代化学, 476, 45-50, 東京化学同人(2010)
14) Glycan receptor for influenza virus
Open Antimicobial Agents J. 2, 26-33 (2010)
15) Structure and function of glycoconjugates involved in dengue virus infection.
Seikagaku 82, 751–755 (2010)
16) スルファチドによるインフルエンザA型ウイルス増殖の促進
Glycoforum,http://www.glycoforum.gr.jp/science/glycomicrobiology/GM05/GM05J.html,
SEIKAGAKU CORPORATION (2010)
17) Role of sulfatide in virus infection and replication.
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY (TIGG), Official Journal of the Japanese Society of Carbohydrate Research, Gakushin Publishing 学進出版, in press (2009)
18) Role of membrane rafts in viral infection. BENTAM OPEN, The Open Dermatology Jounal 3, 165-181 (2009)
19) パンデミックインフルエンザウイルスの出現とノイラミニダーゼの酸性安定性 -Emergence of pandemic influenza viruses and low-pH stability of neuraminidase-
THE LUNG perspectives Vol. 17 No. 4, p. 83-88、株式会社メディカルレビュー社(2009)
20) インフルエンザウイルス感染におけるスルファチドの機能共立出版 蛋白質 核酸 酵素 糖鎖情報の独自性と普遍性、Vol. 53 No. 12、pp.1676-1682 (2008)
21) インフルエンザウイルス感染におけるスパイク糖タンパク質とシアロ複合糖質の役割
実験医学 波及・深化する糖鎖研究25 (7) p. 30-36 (2007)
22) Virus Infection and Lipid Rafts.
Biol. Pharm. Bull. 29, 1538-1541 (2006)
23) 抗インフルエンザウイルス薬の開発について.
呼吸器科 10(1), 37-41 (2006)
24) トリ型インフルエンザインフルエンザウイルスの変異と病原性.
日本胸部臨床 印刷中
25) ウイルスとシアリダーゼ.
生化学 78, 409-413 (2006)
26) パンデミックインフルエンザA型ウイルスノイラミニダーゼの構造と機能.
遺伝子医学 MOOK 糖鎖と病気 pp. 261-266 (2005).
27) インフルエンザウイルスの変異(進化)とヒトへの感染成立―予防と治療―.
今日の移植 17, pp. 375-381 (2004).
28) パラインフルエンザウイルスの選択的感染阻害薬の開発研究.
医学のあゆみ 201, pp. 259 (2002).
29) パラインフルエンザウイルス感染を阻害する新規シアル酸誘導体の開発.
バイオサイエンスとインダストリー  60, pp. 22-25, (2002).
30) インフルエンザウイルスはどのように感染するか
化学と生物、35, PP. 339-345, (1997).
31) HBV感染におけるウイルス表面抗原蛋白質の役割―ヒト肝臓シアロ糖蛋白質のHBVレセプターとしての機能」
日本臨床、53巻(増刊:分子肝炎ウイルス病学―基礎・臨床・予防、下巻)pp. 132-137, (1995).

○著書
1) インフルエンザ・かぜ予防. 新板茶の機能
新版 茶の機能(企画:日本茶業中央会)pp.151-159 (2013)
2) レーニンジャーの新生化学 第5版(分担訳者)
廣川書店 (2010)
3) 酵素ハンドブック(八木達彦、福井俊郎、一島栄治、鏡山博行、虎谷哲夫編集)
朝倉書店(東京) (2008)
4) 感染症と栄養
免疫と栄養(横越英彦 編著 分担
幸書房 (2006)
5) ガングリオシド研究法(鈴木康夫、安藤 進著 分担)
学会出版センター(1995)


教育・研究に対する考え方

教育:講義と実習を通じて生命現象の巧みさとすばらしさを教授し、薬学の分野に広く貢献できる人材を教育したい。
研究:複合糖質が担う生物学的機能を分子レベルで解明し、複合糖質が関わる感染症やがんなどの疾病の診断および治療薬の開発に貢献したい。


研究シーズ集に関するキーワード

ウィルス感染症、脳機能、記憶、がん、糖鎖、シアル酸、診断薬、機能性食品、治療薬


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